Publications
2025
Sex-specific machine learning classification models improve outcome prediction for abdominal aortic aneurysms
Kerr KE, Sen I, Gueldner PH, Tallarita T, Wildenberg JC, Liang NL, Vorp DA, Timothy K. Chung. Biology of Sex Differences, 2025.
Stress prediction based on neural network
Timothy K. Chung, Vorp DA. Patent App. 19/239,703, 2025.
Optimizing Predictive Performance Without Sacrificing Explainability: Comparing Logistic Regression and Ensemble Decision Trees for Abdominal Aortic Aneurysm Repair Outcomes
Jeon BB, Kottakota AK, Kerr KE, Gueldner PH, Guffey MJ, Sen I, Liang NL, Vorp DA, Timothy K. Chung. JVS-Vascular Insights, 2025.
The evolving regulatory landscape for artificial intelligence-enabled devices in the United States
Liang NL, Guffey M, Jeon B, Vorp DA, Timothy K. Chung. JVS-Vascular Insights, 2025.
Development of Machine Learning Models to Predict Postoperative Outcomes After AAA
Eslami M, Abou Ali A, Timothy K. Chung. Journal of Vascular Surgery, 2025.
Magnetic Delivery System and Hydrogel Fixative for Therapeutic Cells
Vorp DA, Ramaswamy AK, Weinbaum JS, Blose KJ, Timothy K. Chung, Kickliter T, Baruch Y, Curci JA. Patent App. 19/082,900, 2025.
Predicting non-invasive mechanical nonlinearity using Artificial Intelligence leveraging ex-vivo and in-vivo pressure-dependent imaging
Vande Geest JP, Timothy K. Chung, Joy J, Geno M, Schwantes G, Danias J, Wollstein G. IOVS, 2025.
Enhancing Longitudinal Predictions of Retinal Fiber Layer Thickness with Mechanical Nonlinearity
Timothy K. Chung, Vande Geest JP, Joy J, Geno M, Schwantes G, Danias J, Wollstein G. IOVS, 2025.
Devices, systems and methods for vessel ligation
Darvish CJ, Timothy K. Chung, et al. Patent App. 18/937,726, 2025.
Artificial intelligence-based machine learning protocols enable quicker assessment of aortic biomechanics: A case study
Gueldner PH, Kerr KE, Liang N, Timothy K. Chung, Tallarita T, Wildenberg J, Beckermann J, Vorp DA, Sen I. JVS Cases, Innovations and Techniques, 2025.
Augmented reality visualization of biomechanical wall stresses on abdominal aortic aneurysms using artificial intelligence
Timothy K. Chung, Gueldner PH, Kottakota AK, Hangey CN, Lee JY, Liang NL, Vorp DA. Science Talks, 2025.
Stress prediction based on neural network
Timothy K. Chung, Vorp DA. US Patent 12,329,546, 2025.
Development of a method to achieve antegrade in situ fenestration of endovascular stent grafts in abdominal aortic aneurysms
Darvish CJ, Lagerman NP, Virag O, Parks H, Pandya YK, Eslami MH, Vorp DA, Timothy K. Chung. JVS Cases, Innovations and Techniques, 2025.
Aneurysm modeling and risk prediction
Timothy K. Chung, Vorp DA. Patent App. 18/716,079, 2025.
Magnetic delivery system and hydrogel fixative for therapeutic cells
Vorp DA, Ramaswamy AK, Weinbaum JS, Blose KJ, Timothy K. Chung, Kickliter T, Baruch Y, Curci JA. US Patent 12,280,112, 2025.
2024
Endovascular orifice detection device for accurate fenestrated stent graft deployment
Eslami MH, Vorp DA, Timothy K. Chung. US Patent 12,070,294, 2024.
Preliminary report demonstrating feasibility of utilizing AI for imaging and biomechanical study of aortic aneurysms
Sen I, Tallarita T, Kerr K, Gueldner P, Wildenberg J, Liang N, Vorp D, Timothy K. Chung. Journal of Vascular Surgery, 2024.
Repeatability of In-Vivo Measurement of Lamina Cribrosa’s Biomechanics
Schwantes GC, Kamen L, Zambrano R, Timothy K. Chung, Lee T-F, Danias J, Vande Geest J, Wollstein G. IOVS, 2024.
Aortic tissue stiffness and tensile strength are correlated with density changes following proteolytic treatment
Gueldner PH, Darvish CJ, Chickanosky IKM, Ahlgren EE, Fortunato R, Timothy K. Chung, et al. Journal of Biomechanics, 2024.
In Vivo Longitudinal Biomechanical Changes of the Lamina Cribrosa Under Chronic Elevated Intraocular Pressure
Schwantes GC, Kamen L, Zambrano R, Timothy K. Chung, Danias J, Vande Geest JP, Wollstein G. IOVS, 2024.
An artificial intelligence based abdominal aortic aneurysm prognosis classifier to predict patient outcomes
Timothy K. Chung, Gueldner PH, Aloziem OU, Liang NL, Vorp DA. Scientific Reports, 2024.
A comparative study of machine learning and algorithmic approaches to automatically identify the yield point in normal and aneurysmal human aortic tissues
Timothy K. Chung, Kim J, Gueldner PH, Vorp DA, Raghavan ML. Journal of Biomechanical Engineering, 2024.
2023
The regulatory environment for artificial intelligence-enabled devices in the United States
Liang NL, Timothy K. Chung, Vorp DA. Seminars in Vascular Surgery, 2023.
Mechanical and matrix effects of short and long-duration exposure to BAPN in elastase-induced model AAA in mice
Gueldner PH, Marini AX, Li B, Darvish CJ, Timothy K. Chung, Weinbaum JS, Curci JA, Vorp DA. JVS-Vascular Science, 2023.
2022
An objective and repeatable sac isolation technique for comparing biomechanical metrics in abdominal aortic aneurysms
Timothy K. Chung, Gueldner PH, Kickliter TM, Liang NL, Vorp DA. Bioengineering, 2022.
Artificial Intelligence Framework to Predict Wall Stress in Abdominal Aortic Aneurysm
Timothy K. Chung, Liang NL, Vorp DA. Applications in Engineering Science, 2022.
2021
Magnetic Delivery System and Hydrogel Fixative for Therapeutic Cells
Vorp DA, Ramaswamy AK, Weinbaum JS, Blose KJ, Timothy K. Chung, Kickliter TM, et al. US 20,210,338,816, 2021.
Aneurysm Modeling and Risk Prediction
Timothy K. Chung, Vorp DA. US Patent 63/285,571, 2021.
Design and manufacture of two experimental test benches for the in vitro assessment of a method to perform in situ fenestration of stent grafts
Lagerman NP, Timothy K. Chung, Eslami MH, Vorp DA. Undergraduate Research at the Swanson School of Engineering, 2021.
Biomechanical and histological data from abdominal aortas harvested in autopsy
Gomes VC, da Silva LFF, Raghavan ML, Gomes J, Silvestre GC, Queiroz A, et al., Timothy K. Chung. Data in Brief, 2021.
Experimental study of rupture pressure and elasticity of abdominal aortic aneurysms found at autopsy
Gomes VC, Raghavan ML, da Silva LFF, Gomes J, Silvestre GC, Queiroz A, Marques MA, Zyngier SP, Timothy K. Chung, da Silva ES. Annals of Vascular Surgery, 2021.
2020
Stress Prediction Based on Neural Network
Timothy K. Chung, Vorp DA. PCT/US2020/055,511, 2020.
Endovascular Orifice Detection Device for Accurate Fenestrated Stent Graft Deployment
Timothy K. Chung, Eslami MH, Vorp DA. PCT/US2020/028,791, 2020.
Development of a semi-automated, bulk seeding device for large animal model implantation of tissue engineered vascular grafts
Cunnane EM, Lorentz KL, Soletti L, Ramaswamy AK, Timothy K. Chung, Haskett DG, et al. Frontiers in Bioengineering and Biotechnology, 2020.
2019
Adventitial Delivery of Therapeutic Cells for Localization in Porcine Aortas
Kickliter TM, Timothy K. Chung, Ramaswamy AK, Weinbaum JS, Vorp DA. Ingenium, 2019.
Investigation of the observed rupture lines in abdominal aortic aneurysms using crack propagation simulations
Attarian S, Xiao S, Timothy K. Chung, da Silva ES, Raghavan ML. Journal of Biomechanical Engineering, 2019.
Iron nanoparticle contrast enhanced microwave imaging for emergent stroke: A pilot study
Hudson JS, Timothy K. Chung, Prout BS, Nagahama Y, Raghavan ML, Hasan DM. Journal of Clinical Neuroscience, 2019.
Cerebral aneurysm wall stress after coiling depends on morphology and coil packing density
Pichamuthu JE, Feroze RA, Timothy K. Chung, Jankowitz BT, Vorp DA. Journal of Biomechanical Engineering, 2019.
2017
Study of multi-axial failure properties of planar biological soft tissues
Timothy K. Chung. Book/dissertation, 2017.
Does elevated wall tension cause aortic aneurysm rupture? Investigation using a subject-specific heterogeneous model
Timothy K. Chung, da Silva ES, Raghavan SML. Journal of Biomechanics, 2017.
Novel Methods and Considerations for Addressing Aortic Arch Hypoplasia and Coarctation
Cavanaugh NB, Nellis JR, Timothy K. Chung, Holgren SE, Tcheng JW, Carlson AM, Torres JE, Raghavan ML, Turek JW. 2017.
Modeling outcomes: modified aortic arch advancement for neonatal hypoplastic arch
Nellis JR, Timothy K. Chung, Agarwal N, Torres JE, Holgren SE, Raghavan ML, Turek JW. Innovations, 2017.
2015
Systems and Methods for Alignment of the Eye for Ocular Imaging
Abramoff M, Talmage E, Clark B, Dehoog E, Timothy K. Chung. US Patent 9,814,386 B2, 2015.
2013
Heterogeneous finite element stress analysis of abdominal aortic aneurysms: Comparison between ruptured and unruptured lesions
Timothy K. Chung. Master’s thesis, The University of Iowa, 2013.